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pentobarbital will minimize the extent or outcome of pantoprazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.Minimal (1)pentobarbital will lessen the extent or impact of paclitaxel protein bound by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.fentanyl iontoph